| External Bleeding (Laceration / Cut) | Cardiovascular & Skin | High | Rapid blood volume loss (L/m), dripping blood indicator on limb, declining blood pressure | Dressing (-0.675L/m over 12 wraps), Sterilized dressing (-45% max bleed), Plastic dressing (-72% max bleed), or Alginate dressing (-72.5% max bleed) | Tourniquet (halts arterial limb bleeding immediately), Medical suture, Wound glue, or Clotting mush | Apply dressing wraps in Health Panel; if using Medical suture, complete the stitching minigame | Hypovolemic shock, loss of consciousness, cardiac arrest, and bleedout death | INT 1 (Dressing) / INT 9 (Tourniquet) |
| Internal Bleeding | Cardiovascular & Internal Organs | Critical | Hidden blood volume drop without external skin laceration after blunt trauma, explosion, or high-velocity fall | Procoagulant syringe (craftable at INT 14 from Bunchunks) or L.R.D. Serum injection | Blood bag / Red blood bag transfusion or Saline / Ringer's solution IV to maintain blood volume | Inject Procoagulant or L.R.D. via syringe into affected torso/limb in Health Panel | Silent blood loss leading to vascular collapse and asystole | INT 11 (L.R.D.) / INT 14 (Procoagulant) |
| Hemothorax (Collapsed / Blood-Filled Lung) | Thorax & Respiratory | Critical | Blood pooling in pleural cavity after chest trauma, plunging bloodOxygen, suffocation moodle | Chest drain applied to the Thorax in the Health Panel | Oxygen crystal shard, Oxyline injection, or L.R.D. Serum to sustain oxygenation | Chest drain insertion on Thorax to evacuate pleural blood and restore lung capacity | Rapid hypoxia, brain damage from oxygen deprivation, and death | INT 9 (Chest drain) |
| Barotrauma (High Air Pressure Trauma) | Thorax, Lungs & Ears | High | Occurs in lower half of Layer 9 (Geothermal Vents) and throughout Layer 10 (Where We Must Reach) as ambient air pressure rises | Advanced scuba diving gear or rapid descent/extraction via High-Powered Drill Pod | L.R.D. Serum, Chest drain, and Painkillers to mitigate organ and eardrum rupture | Equip pressure-resistant diving gear and minimize time spent stationary in Layer 10 | Pulmonary rupture, hearing loss, internal hemorrhage, and suffocation | INT 9 (Advanced scuba diving gear) |
| Bone Fracture | Skeletal & Limbs | Moderate | Audible bone snap on fall or blunt impact, severe pain on movement, reduced limb speed/strength, visible in Health Panel (or with Unchipped) | Splint or Carcass splint immobilized on the fractured limb, or Bone welding tool for instant repair | Dressing (-7m 45s fracture heal time for 12 wraps), Sterilized dressing (-20% max heal time), Plastic dressing (-30% max heal time) | Apply Splint directly or use Bone welding tool (requires L.R.D. Serum & Circuit board) | Crippled mobility, recurring internal tissue damage, and severe agony when walking or climbing | INT 4 (Splint recognize) / INT 8 (Splint craft) |
| Joint Dislocation | Skeletal & Limbs | Moderate | Limb joint popped out of socket from fall, grabber-shroom pull, or explosion; sharp pain and loss of limb function | Manual joint reduction minigame in the Health Panel, followed by Dressing or Limb wraps | Fentanyl syringe, Morphine syringe, or Painkillers prior to reduction to prevent pain shock | Limb dislocation pull-and-align minigame (RES above 10 reduces hand shakiness by 6% per level) | Unable to swing weapons, climb ropes effectively, or bear weight without extreme pain | INT 0 (Manual reduction) |
| Local Wound Infection | Immune & Skin | Moderate | Dirty lacerations exposed to cave water, soil, or creature bites; rising local infection bar on limb | Alcohol, Antiseptic bottle, Antiseptic mush, Relief cream, or Bleach applied to wound | Sterilized dressing (900s disinfection) or Alginate dressing (800s disinfection) | Pour or spray disinfectant fluid onto limb in Health Panel before bandaging | Escalates into systemic Sepsis across the bloodstream | INT 5 (Antiseptic mush) |
| Systemic Sepsis | Immune & Cardiovascular | Critical | Untreated local wound infection spreads to bloodstream; fever, toxicosis, organ decay, and plummeting blood pressure | Ceftriaxone syringe (injected) or Antibiotics bottle (oral/applied) | Emergency limb Amputation if a single necrotic limb is driving fatal sepsis and no antibiotics remain | Inject Ceftriaxone syringe or perform surgical Amputation minigame with Machete/Bonesaw + Tourniquet | Multi-organ failure, septic shock, and guaranteed death | INT 7 (Antibiotics bottle) / INT 10 (Ceftriaxone syringe) |
| Cardiac Fibrillation / Arrhythmia | Cardiovascular & Heart | Critical | Erratic ECG waveform, fluttering heart rate, rapid loss of consciousness after electric shock,Coil trap, or severe hypoxia | Automated external defibrillator (AED) or Manual defibrillator applied to Thorax | Amiodarone bottle/injection or Epinephrine to stabilize cardiac rhythm | AED pad placement minigame or Manual defibrillator charge-estimation minigame (INT narrows POW.EST range by 5 per level) | Immediate progression to Asystole (flatline) and brain death | INT 6 (AED) / INT 10 (Manual defibrillator) |
| Asystole & Hypovolemic Shock | Cardiovascular & Heart | Critical | Flatline heart rhythm or critically low blood volume (<40%), unconsciousness, rapid brain health deterioration | Epinephrine injection + CPR / Auto-pump + immediate Blood bag or Saline/Ringer's solution volume restoration | Vasopressin to elevate dangerously low blood pressure | Thorax resuscitation and intravenous fluid bag infusion | Irreversible brain death within seconds | INT 8 (Blood bag / Epinephrine) |
| Opiate Overdose & Addiction | Neurological & Respiratory | High | Opiate meter in Health Panel spikes after excessive Fentanyl, Heroin, Morphine, or Opium; respiratory depression and coma | Naloxone syringe (immediate opioid antagonist reversal) or Naltrexone bottle | Manual ventilation / Oxygen support until opiate concentration metabolizes | Inject Naloxone syringe directly into any limb via Health Panel (Default safe Fentanyl dose is 2% / 0.25mL) | Respiratory arrest, bloodOxygen collapse, and hypoxic brain death | INT 8 (Naloxone syringe) |
| Radiation Sickness | Cellular & Systemic | High | Radiation icon fills up in Layer 4 (Wasteland), near Radioactive barrels, Spent fuel, or Layer 7 fungi; nausea, nausea sickness, and cell decay | Anti-rad bottle (Antirad fluid) or Soothing crystal shard | Geiger counter to detect radiation zones early; Unchipped mode disables the rad-line HUD warning | Drink or inject Anti-rad fluid and evacuate radioactive tile radius | Progressive internal bleeding, immune collapse, and unhealable cellular necrosis | INT 6 (Anti-rad bottle) |
| Hypothermia & Wetness Freezing | Thermoregulation | High | Core body temperature drops below 35°C in Layer 6 (Frozen Chasm, -30.6°C avg) or while sleeping wet in Layer 7 (Fungal Pools) | Campfire (20 Heat source quality), Ion space heater, Life-pod heater, or Heatfern proximity | Wearable insulation (Hoodie, Scarf, Arm warmers, Balaclava) and Hot sauce / warm Soup | Place Campfire or shelter inside a Life-pod before sleeping | Shivering stamina drain, frostbite limb damage, lethargy, and freezing death | INT 4 (Campfire) |
| Hyperthermia & Thermal Burns | Thermoregulation & Skin | High | Core temperature spikes above 40°C in Layer 9 (Geothermal Vents, up to 40.8°C) or Layer 3 (Dried Desert), or from Magma/Fire contact | Ice pack, Coldpuff plant, Relief cream, or immersion in cool Clean water | Alginate dressing and Sterilized dressing for burn skin damage; remove heavy insulating clothing | Apply Ice pack / Relief cream and hydrate with Clean water or Sports drink | Heatstroke, rapid dehydration, brain damage, and burn shock | INT 9 (Relief cream) |
| Brain Trauma & Hypoxic Encephalopathy | Neurological & Brain | Critical | Head impact, skullcrusher trap, stroke, or prolonged hypoxia; visual distortion, speech/UI garbling, motor loss | Braingrow bottle / Braingrow fluid, L.R.D. Serum, or 0.0.7-Emergency Rejuvenation chip | Bicycle helmet, Riot helmet, or Makeshift helmet to prevent head trauma; Streptokinase for ischemic stroke clots | Administer Braingrow or L.R.D. Serum and restore bloodOxygen above 90% | Permanent neurological deficits, capture during Escape Ending, or immediate death at 0% brain health | INT 11 (L.R.D. / Braingrow) |
| Embedded Shrapnel & Glass Shards | Limbs & Soft Tissue | Moderate | Ongoing bleeding and pain after Landmine, Gunmine, Turret gunshot, or stepping on broken glass | Tweezers to extract shrapnel/bullet, followed by Antiseptic and Dressing | Fentanyl syringe or Local anesthetic prior to extraction; Tactical boots to prevent foot glass injuries | Shrapnel extraction minigame in Health Panel using Tweezers (high RES steadies hand tremor) | Bandages cannot fully stop bleeding while shrapnel remains lodged; high infection risk | INT 3 (Tweezers) |
| Venom & Toxicosis | Systemic & Bloodstream | High | Venom meter rises in Health Panel (added in Release 1.0) after spider/creature bites or toxic ingestion | Antivenom fluid / Antiserum syringe or Digestion crystal shard (reduces toxicosis in 1.0) | Saline IV hydration and Charcoal to purge ingested toxins | Inject Antivenom / Antiserum syringe directly into bitten limb | Systemic paralysis, internal organ decay, and fatal neurotoxicity | INT 8 (Antivenom / Antiserum) |
| Irreversible Limb Necrosis / Crushing Trap | Limbs & Surgical | Critical | Limb completely mangled or gangrenous; in Release 1.0 amputation can also be performed on non-infected limbs and both legs | Tourniquet above limb + surgical Amputation with Machete/Cutting tool + Cauterization/Sterilized dressing + Prosthesis (Peg limb / Steel prosthesis / P.E.O. limb) | Morphine or Fentanyl analgesia before cutting to prevent lethal agony shock | Amputation sawing minigame (made less punishing in Release 1.0), followed by attaching a Prosthesis | Exsanguination during surgery if no Tourniquet is applied, or death from spreading gangrene | INT 9 (Tourniquet) / INT 12 (Machete) |